摘要
目的了解门诊患者使用塞来昔布情况,以促进临床安全合理用药。方法利用医院信息管理系统(HIS系统)收集蚌埠市第三人民医院2017年1—12月收治使用塞来昔布的698例门诊患者的临床资料,统计患者性别、年龄、就诊科室及合并疾病,并依据药品说明书以及国内外循证医学研究结果对塞来昔布的适应证、用法用量和联合用药情况进行分析。结果门诊698例使用塞来昔布患者中,男336例(48.1%),女362例(51.9%),平均年龄(63.3±19.0)岁;骨科开具处方数最多(512例,73.4%);处方诊断以骨关节炎(OA)最为多见(269例,38.5%);联合使用最多的药物为氨基葡萄糖(52例,7.4%)。结论该院门诊塞来昔布的使用基本合理,部分处方有超说明书用药现象,临床医师与药师应重视塞来昔布合理应用及用药风险,保障患者用药安全合理。
Objective To know the use of celecoxib of outpatients in a hospital,in order to promote their safe and rational drug use. Methods The hospital information management system was used to collect the clinical data of 698 patients with celecoxib hospitalized in Bengbu Third People's Hospital from 1 to December 2017. The sex, age, medical department and combined diseases were statistically analyzed, and celecoxib was made according to the drug instructions and the results of the evidence-based medicine study both at home and abroad. Indications,dosage and combination of drugs were analyzed. Results A total of 698 outpatients using celecoxib, including 336 men and 362 women, mean age 63.3±19.0; the maximum number of prescriptions were issued by Orthopedics(512 cases, 73.4%); the most commonly prescribed diagnostic was osteoarthritis(269 cases, 38.5%); most of the drug is used in combination was glucosamine(52 cases, 7.4%). Conclusion The use of celecoxib in this hospital outpatients was reasonable, some prescriptions were questionable in terms of dose and combination therapy, clinicians and pharmacists should pay attention on drug risks of celecoxib to ensure safety and rationality.
作者
陈静
朱玲娜
CHENG Jing;ZHU Ling-na
出处
《中国药物经济学》
2018年第8期25-28,共4页
China Journal of Pharmaceutical Economics