1329例婴幼儿25-羟基维生素D水平及其影响因素

25-Hydroxyvitamin D Levels in the serum and its influencing factors among 1329 infants and children

目的调查1329例婴幼儿血清25-羟基维生素D水平及其影响因素。方法选择2017年1月-12月在新疆伊犁州奎屯医院门诊及住院的(0~14)岁婴幼儿,采用电化学发光免疫分析法检测血清25-羟基维生素D水平。分析血清25-羟基维生素D水平与性别、年龄及季节的相关影响因素。结果 1329例参与检测的婴幼儿中,男性25-羟基维生素D不足占31.66%,高于女性组的26.31%,差异具有统计学意义(P <0.05);各年龄组的25-羟基维生素D水平差异均有统计学意义(P <0.05);夏秋两季婴幼儿血清25-羟基维生素D水平缺乏的发生率明显低于冬春两季,差异具有统计学意义(P <0.05)。结论 1329例(0~14)岁婴幼儿维生素D仍有一定的缺乏率,应结合当地气候及饮食特点,继续采取积极措施提高维生素D水平。

Objective To investigate 25-Hydroxyvitamin D Level in the serum of 1329 infants and children and its influencing factors. Method The infants and children between 0 and 14 years old who were in hospital or in the outpatient clinic of Kuitun Hospital of Yili State, Xinjiang in the whole year of 2017 were selected, then electrochemiluminescence immunoassay（ECLIA） was used to examine the 25-Hydroxyvitamin D Level in the serum, and the relationships between 25-Hydroxyvitamin D Level and gender, age, season and other relevant influential factors were analyzed. Result Among 1329 infants and children, deficiency in 25-Hydroxyvitamin D in the male group accounted for 31.66%, which was higher than that in female group accounting for 26.31%, and the difference was statistically significant（P〈0.05）; The differences of 25-Hydroxyvitamin D Level among the groups with different ages were all statistically significantly different（P〈0.05）; The incidence of deficiency in 25-hydroxyvitamin D in infants in summer and autumn were obviously lower than those in winter and spring（P〈0.05）. Conclusion 1329 infants and children aged between 0 and 14 years old were short of vitamin D more or less. Therefore, it is necessary to take active measures to improve the level of vitamin D according to the local climate and dietary habit.