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粪菌移植治疗现状及其在炎症性肠病中的应用 被引量:7

Current status of fecal microbiota transplantation and its application in inflammatory bowel disease
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摘要 粪菌移植(FMT)作为一种针对肠道微生态的疗法,为诸多疾病的治疗提供了一个新的选择。但这项治疗方案仍处于起步阶段,诸多可能影响FMT疗效的因素尚不明确,输注剂量和频次、输注途径、供体筛选、输注液制备方法以及潜在风险需要进一步研究。炎症性肠病(IBD)的病因及发病机制尚不明确,现有的治疗药物包括氨基水杨酸、激素、免疫抑制剂等。近年的多项研究表明,FMT安全且有助于诱导IBD症状缓解。该文就FMT的研究现状及其在IBD中的应用状况作一综述。
出处 《国际消化病杂志》 CAS 2018年第5期294-296,305,共4页 International Journal of Digestive Diseases
基金 上海市第一人民医院临床研究创新团队建设项目(CTCCR-2016B03) 上海申康医院发展中心临床科技创新项目(SHDC12017X09)
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