白银地区体检人群Hp阳性率与年龄、性别及糖脂代谢的关系分析

Relationships between Hp Positive Rate and Age and Gender in Physical Examination Populations in Baiyin District

目的探讨白银地区体检人群幽门螺旋杆菌(Hp)阳性率情况与年龄、性别及糖脂代谢的关系。方法选取2015年1月-2017年12月白银地区体检人群18 722例,检测Hp感染率。结果 16 722例健康体检者中7092例感染Hp,感染率为42.41%;男性健康体检者中Hp感染率为48.63%,明显高于女性(P<0.05); 20～29岁、30～39岁、40～49岁、50～59岁和60～70岁Hp感染率分别为31.78%、38.49%、41.68%、49.18%和65.93%,随年龄增加,Hp感染率升高(P<0.05); Hp感染者空腹血糖(FBG)为(4.98±1.22) mmol/L,明显高于无Hp感染者(P<0.05),而高密度脂蛋白胆固醇(HDLC)为(1.10±0.35) mmol/L,明显低于无Hp感染者(P<0.05)。结论白银地区体检人群Hp阳性率较高,阳性率在性别、年龄分布中有所差异,同时Hp感染对糖脂代谢有一定影响。

Objective To explore the relationships between the positive rate of Helicobacter pylori（ Hp） and age and gender in physical examination populations in Baiyin District.Methods A total of 16,722 cases of physical examination in Baiyin District between January 2015 and December 2017 were selected to detect the Hp infection rate. Results Among the 16,722 health examinees,7092 cases were infected with Hp,so the infection rate was 42.41%. The rate of Hp infection was 48.63% in male health examinees,which was significantly higher than that in female ones（ P〈0.05）. The rates of Hp infection among populations aged 20 to 29,30 to 39,40 to 49,50 to 59 and 60 to 70 were 31.78%,38.49%,41.68%,49.18% and 65.93%,respectively. The rate of Hp infection increased with the age of patients（ P〈0.05）. The fasting blood glucose（ FBG） of Hp infected people was（ 4.98±1.22） mmol/L,which was significantly higher than that of those without Hp（ P〈0.05）. The level of high density lipoprotein cholesterol（ HDL-C） was（ 1.10±0.35） mmol/L,significantly lower than that of those without Hp infection（ P〈0.05）.Conclusion The positive rate of Hp is not only relatively high in the physical examination populations in Baiyin District,but different in gender and age distribution. Hp infection has some effect on glycolipid metabolism.