影响宁波中老年人群患甲状腺结节的危险因素分析

Analysis of risk factors affecting thyroid nodules in middle-aged and elderly people in Ningbo

目的调查影响宁波地区年龄≥45岁中老年人群患甲状腺结节的相关危险因素。方法选取宁波2014年12月～2017年12月期间某大型国有企业体检中完成甲状腺B超检测及血压、血糖、血脂常规、尿酸、尿糖等实验室检查的中老年人群3395例,建立Logistic回归模型进行多因素分析。结果 3395例中老年人群甲状腺结节总患病率为46.98%;经Logistic多因素回归分析,高龄女性、糖尿病、长期吸烟、肥胖、高血压、高尿酸、高血脂均是甲状腺结节发生的危险因素(P<0.05)。结论高龄、女性、高血压病、糖尿病、吸烟、肥胖、高血脂、高尿酸均是患甲状腺结节的高危因素,可早期采取相应的科学干预措施积极进行预防。

Objective To investigate the risk factors affecting thyroid nodules in middle-aged and elderly people aged≥45 years in Ningbo. Methods A total of 3395 middle-aged and elderly people who completed thyroid B-ultrasound examination and blood pressure, blood glucose, blood lipid routine, uric acid, urine glucose and other laboratory tests in a large state-owned enterprise from December 2014 to December 2017 were selected. Logistic regression model was established for multivariate analysis. Results The total prevalence rate of thyroid nodules in 3395 middle-aged and elderly population was 46.98%. Logistic multivariate regression analysis showed that oldwomen, diabetes, long-term smoking, obesity, hypertension, high uric acid and hyperlipidemia were the risk factors of thyroid nodules（P〈0.05）. Conclusion Old age, female, hypertension, diabetes, smoking, obesity, hyperlipidemia, and high uric acid are all risk factors for thyroid nodules. Early scientific interventions can be taken to prevent the occurrence of thyroid nodules.