摘要
化疗在治疗恶性肿瘤的同时可造成卵巢功能的损伤,引起闭经和不孕。对不同的化疗药物损伤机制的了解,可使我们有针对性地实现生育力的保护。已证实有多种方法及药物可保护卵巢功能,实现生育力的保护。本文将对化疗药物对卵巢功能的损伤机制及生育力保护的相关进展作一综述。
Chemotherapy can induce ovarian damage while treating malignant tumor, which causes amenorrhea and infertility. The understanding of the mechanisms of chemotherapy-induced ovarian damage may lead to targeted treatments to preserve fertility. It has been proved that there are many methods and medicines to protect ovarian function and realize the preservation of fertility. This article reviews the mechanisms of chemotherapy-induced ovarian damage and the progress of fertility preservation.
作者
付子洁
李晓冬
Fu Zijie;Li Xiaodong(Department of Gynecology,the Second Hospital of Hebei Medical University,Shijiazhuang 050000,China)
出处
《中华生殖与避孕杂志》
CAS
CSCD
北大核心
2018年第9期737-740,共4页
Chinese Journal of Reproduction and Contraception
关键词
化疗
卵巢功能
生育力保护
Chemotherapy
Ovarian fimction
Fertility preservation
