摘要
Influenza virus is a long-lasting and severe threat to human health. Seasonal flu epidemics, which are caused by the co- circulating influenza A viruses （IAVs） and influenza B viruses （IBVs）, occur annually and lead to tens of millions of respiratory illnesses and up to half a million human deaths worldwide each year （Ginsberg et al., 2009）. Influenza pandemics are more devastating. The 2009 swine-originated H1N1 virus, which caused the latest influenza pandemic, spread from Mexico and U.S.
Influenza virus is a long-lasting and severe threat to human health. Seasonal flu epidemics, which are caused by the co- circulating influenza A viruses （IAVs） and influenza B viruses （IBVs）, occur annually and lead to tens of millions of respiratory illnesses and up to half a million human deaths worldwide each year （Ginsberg et al., 2009）. Influenza pandemics are more devastating. The 2009 swine-originated H1N1 virus, which caused the latest influenza pandemic, spread from Mexico and U.S.
基金
We gratefully thank Dr. Jun Wu of the Institute of Microbiology, Chinese Academy of Sciences, for helpful suggestions. This work was supported by grants from the National Key R＆D Program of China （2016YFD0500206, 2017YFD051105, 2016YFC1200803, and 2016YFC1201303）, National Natural Science Foundation of China （Grant Nos. 31572526, 31402216 and 31630079）, National Defense Foundation of China （Grant No. 17-163-12-ZT-005-041-01 ）, the Southeast Asia Biodiversity Research Institute, Chinese Acad- emy of Sciences （Y4ZK111B01）. Wenjun Liu and Po Tian are the principal investigators of the NSFC Innovative Research Group （Grant No. 81621091）.
