大豆磷脂软胶囊辅助降血脂功能研究

Function of granulesten soft capsule in reducing blood lipid

目的探讨大豆磷脂软胶囊辅助降低血脂功能。方法将50只大鼠随机分成5组,空白对照组大鼠给予基础饲料,其余各组给予高脂饲料喂养,各剂量组给予不同剂量的大豆磷脂软胶囊,模型对照组和空白对照组大鼠给予等体积的植物油, 30 d后观察大鼠体重及血脂水平的变化。结果模型对照组大鼠血清总胆固醇(total cholesterol, TC)、甘油三酯(trilaurin, TG)、体重显著高于空白对照组,差异均有统计学意义(P<0.05);各个剂量组大鼠血清TG、体重均低于高脂对照组,差异均有统计学意义(P<0.05)。结论大豆磷脂软胶囊通过降低血清甘油三酯达到辅助降血脂功能。

Objective To investigate the function of granulesten soft capsule in reducing blood lipid auxiliary. Methods Fifty rats were randomly divided into 5 groups, the control group was given a basic diet, and the other groups were fed with high fat diet. Different doses of granulesten soft capsules were administered to each dose group, and the model control group and the blank control group rats were given an equal volume of vegetable oil. Changes in body weight and blood lipid levels were observed after 30 d. Results The serum total cholesterol（TC）, trilaurin（TG） and body weight of the model control group were significantly higher than those of the blank control group（P0.05）. The serum TG and body weight of the rats in each dose group were lower than those in the high-fat control group, and the difference was statistically significant（P0.05）. Conclusions Granulesten soft capsules help to lower blood lipids by lowering serum triglycerides.