彩超引导下聚桂醇泡沫硬化剂注射治疗静脉畸形的近期疗效与安全性分析

Safety and Short-term Efficacy of Ultrasound Guided Scleortherapy of Venous Malformations with Lauromacrogol Foam

目的:探讨彩超引导下聚桂醇泡沫硬化剂治疗静脉畸形的可行性,并评价其近期临床疗效及安全性。方法:选取笔者医院整形外科确诊为静脉畸形的患者47例,依据术中彩超和影像学复查病灶消退情况以及病灶颜色、大小的改善程度,采用彩超引导下聚桂醇注射栓塞治疗方案,并进行疗效评价,分析彩超引导下聚桂醇治疗静脉畸形的有效性及安全性。结果:47例患者经彩超引导下聚桂醇注射栓塞治疗共78次,治愈39例,基本治愈5例,有效3例,无效0例,不良反应包括局部皮温升高、疼痛肿胀、皮肤瘀斑,均未出现严重并发症。结论:应用彩超引导下聚桂醇注射治疗静脉畸形安全有效,简单易行,适合临床推广。

Objective To investigate the feasibility of ultrasound guided scleortherapy with Lauromacrogol foam and evaluate the short-term effcacy and safety in the treatment of venous malformation. Methods 47 venous malformations patients were treated with Lauromacrogol foam sclerosing agent under ultrasound guidance. The effect was respectively evaluated depending on the basis of the result of color doppler sonography during the treatment, imaging review of lesions fading condition and the improvement of clinical symptoms,and we also assessed the safety and superiority of percutaneous ultrasound-guided Lauromacrogol sclerotherapy. Results There were 78 times in the treatment of direct percutaneous lauromacrogol foam sclerosing agent injection for 47 patients in total. The results were excellent in 39cases, good in 5 cases, valid in 3 cases and there was no case was invalid. Side effects included the changes of local skin temperature, postoperative pain,swelling and ecchymoses.47 patients had no serious postoperative complications. Conclusion Percutaneous ultrasound-guided Lauromacrogol sclerotherapy is a less-invasive, effective and convenient method, it provides a new and alternative way and is expected to be one of the most important treatments for venous malformations.