热毒宁联合阿奇霉素治疗小儿支气管肺炎的临床疗效观察

Study on the application effect of reduning and azithromycin in the treatment of pneumonia

目的:观察热毒宁联合阿奇霉素治疗小儿支气管肺炎的临床疗效。方法:收集2014年1月—2016年1月治疗的小儿支气管肺炎患儿88例,按照随机数字表法分为观察组与对照组,每组44例。对照组应用阿奇霉素治疗,观察组在应用阿奇霉素的同时加用热毒宁治疗,对比两组的临床疗效。结果:观察组的退热时间、肺部啰音消失时间、咳嗽消失时间、X线肺部阴影消失时间及住院时间均较对照组明显缩短(P <0. 05);观察组治疗总有效率为95. 45%,较对照组的81. 82%显著提高(P <0. 05);观察组的不良反应率为15. 91%,与对照组的11. 36%比较,差异无统计学意义(P> 0. 05)。结论:小儿支气管肺炎应用热毒宁与阿奇霉素联合治疗,能够促进临床症状与体征的消退,疗效优于阿奇霉素单药治疗。

Objective ：To study the clinical efficacy of azithromycin and reduning combined treatment of pneumonia. Methods ： All 88 cases of pneumonia in children hospitalized in our hospital from January 2014 to January were collected and divided into observation group and control group according to the random number table method ,44 eases in each group. Control group with azithromyein treatment and group with azithromyein combined reduning treatment, compared to two groups of clinical curative effect observation. Results ： In the observation group, fever, pulmonary rales disappearance time, cough disappeared time, radiographic disappearance time and hospital stay were significantly shorter than the control group （ P 〈 0.05 ） ; in the observation group,the total effective rate was 95.45% ,compared with the control group 81.82% increased significantly （P 〈 0.05 ）. In the observation group, the adverse reaction rate 15.91% , and the control group 11.36% of the difference,no statistical significance （ P 〉 0.05 ）. Conclusion ： Pneumonia reduning combined with azithromycin treatment can promote regression of clinical symptoms and signs, curative effect due to azithromyein monotherapy.