高压氧对重型颅脑损伤术后患者预后的影响分析

Analysis of the Effect of Hyperbaric Oxygen on the Prognosis of Patients with Severe Craniocerebral Injury

目的分析高压氧对重型颅脑损伤术后患者预后的影响。方法便利收集该院在2014年7月—2016年7月收治的重型颅脑损伤手术患者106例作为研究对象,按照随机偶数奇数法分为对照组(n=53)和实验组(n=53),对照组实施常规治疗,实验组实施高压氧治疗,对两组治疗效果、GCS评分等预后情况进行评比。结果实验组治疗总有效率96.22%显著优于对照组81.13%,组间差异有统计学意义(χ~2=6.014 2,P=0.014 1);对照组术前、术后2 h、术后3个月GCS评分分别为(6.59±1.15)分、(7.40±1.38)分、(12.62±1.59)分;实验组分别为(6.88±1.07)分、(7.65±1.43)分、(9.57±1.46)分;两组术前、术后2 h的GCS评分差异无统计学意义(t=1.344 0,0.915 8,P=0.181 9,0.361 9),但实验组术后3月的GCS评分均明显高于对照组,两组差异有统计学意义(t=10.286 2,P=0.0000)。结论高压氧可显著改善重型颅脑损伤术后患者预后,提高生存质量,具有积极的临床借鉴和推广价值。

Objective To analyze the effect of hyperbaric oxygen on the prognosis of patients with severe head injury. Methods A total of 106 patients with severe eranioeerebral injury who were admitted to the hospital from July 2014 to July 2016 were convenient enrolled. The patients were divided into control group （n=53） and experimental group （n=53） according to random even odd number method. The control group received routine treatment, and the experimental group underwent hyperbaric oxygen therapy to evaluate the prognosis of the two groups, such as treatment effect and GCS score. Results The total effective rate of the experimental group was 96.22%, which was significantly better than that of the control group （81.13%）. The difference between the two groups was statistically significant （X^2=6.014 2,P=0.014 1）. The control group received preoperative, postoperative 2 h, postoperative 3 The GCS scores were （6.59±1.15）points, （7.40±1.38）points, and （12.62 ± 1.59）points, respectively. The experimental group was （6.88 ± 1.07）points, （7.65 ± 1.43）points, and （9.57 ± 1.46）points. There was no significant difference in GCS scores between the two groups before and after surgery （t=1.344 0,0.915 8,P= 0.181 9,0.361 9）, but the GCS scores in the experimental group were significantly higher than those in the control group. There was a statistical difference between the two groups （t=10.286 2, P=0.000 0）. Conclusion Hyperbaric oxygen can significantly improve the prognosis of patients with severe craniocerebral injury and improve the quality of life. It has positive clinical reference and promotion value.