中老年动脉粥样硬化性肾动脉狭窄预测因子分析

Study on clinical predictor of atherosclerotic renal artery stenosis in middile-aged and elderly patients

目的探讨中老年动脉粥样硬化性肾动脉狭窄(ARAS)的预测因子,为进一步筛查ARAS及防治提供依据。方法回顾性分析867例行肾动脉造影患者的临床资料,按造影结果分为ARAS组446例与非ARAS组421例,对与ARAS高度相关的多项临床指标进行统计分析。结果单因素相关分析显示,年龄、脉压、血肌酐水平及50岁以后出现高血压与ARAS相关(P <0.05)。四项变量均进入回归方程,并与ARAS呈正相关(β=0.056、0.032、0.014、0.614)。结论年龄、脉压、血肌酐水平及50岁以后出现高血压是中老年ARAS的预测因子,可以为临床发现易感人群及预防ARAS提供信息。

Objective The aim was to study on clinical predictor of sclerotic renal artery stenosis （ARAS）in middileaged and elderly patients. Methods We retrospective analyzed the data of 867 patients undergoing renal arteriography at General Hospital of PLA between 2008 and 2017. Their mean age was 64.09 ± 7.81years （42-85 years）. According to the results of arteriography,they were divided into two groups,one group was ARAS （n=446）,the other was non-ARAS （n=421）. Their pulse pressure （PP） and multinomial clinical indexes with ARAS were statistical analyzed. Results Single factor correlation and Iogisitic analysis showed that age and PP and plasma creatinine levels （Cr） and new onset of hypertension after 50 years of age were strongly positively related to ARAS （P 〈 0.05）. The age and PP and Cr were a team of continuous variable （β=0.056、0.032、0.014、0.614）. Conclusion Age and PP and Cr and new onset of hypertension after 50 years of age were predictive factor of ARAS in middile-aged and elderly patients. They would give us some information to find and prevent ARAS in clinical practice.