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冠心病患者血清脂联素水平的研究

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摘要 探讨冠心病患者血清中炎性介质脂联素的水平与冠心病患者之间的关系。方法:85例冠心病患者,88例对照组,采用ELASA法测定血清中脂联素的水平,并全部测身高、体重、腰围、臀围,计算腰臀比、腰高比、体重指数。结果:冠心病组和对照组脂联素相比差异具有统计学意义(P=0.00);稳定型冠心病组与急性冠脉综合征组血清脂联素水平相比,差异具有统计学意义(P=0.01)。结论:脂联素可能与腹腔内脂肪量有一定的关系,可反映肥胖、体内炎症情况,同时脂联素可能与冠脉斑块的稳定性可能相关。脂联素是由成熟脂肪细胞分泌的脂肪细胞因子[1],有研究表明,脂联素的水平在肥胖人群、糖尿病及冠心病患者中是显著降低的,因此,推测脂联素可能是对抗动脉粥样硬化的保护性因素[2]。本实验通过分析脂联素的水平,进一步研究脂联素和与冠心病的关系及其临床检测的意义。
出处 《才智》 2013年第14期398-398,共1页 Ability and Wisdom
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