影响慢性阻塞性肺疾病稳定期吸入舒利迭依从性相关因素病例对照研究

Comparative Study on Related Influencing Factors of Inhalation Compliance of Seretide for Chronic Obstructive Pulmonary Disease at Stable Stage

目的探讨影响慢性阻塞性肺疾病稳定期吸入舒利迭依从性的相关因素。方法选取2015年1月—2017年6月该院用吸入舒利迭慢性阻塞性肺疾病稳定期患者90例,对其依从性进行判断,采用自制的调查问卷记录不同依从性患者相关因素上差异。结果 90例慢性阻塞性肺疾病稳定期患者舒利迭吸入治疗依从性好41例(45.56%,41/90),依从性差49例(54.44%,49/90);Logistic回归分析影响慢性阻塞性肺疾病稳定期舒利迭吸入治疗依从性的相关因素:年龄≥70岁(OR=4.70,95%CI:2.33~22.05)、对慢阻肺认知偏差(OR=3.88,95%CI:2.09~19.04)、舒利迭不良反应(OR=3.56,95%CI:1.58~18.23)、医患关系一般(OR=3.02,95%CI:1.23~17.23)。结论慢性阻塞性肺疾病稳定期舒利迭应用过程中年龄、对慢阻肺认知、舒利迭不良反应、医患关系影响了依从性,应实施相应的措施提高舒利迭依从性。

Objective To study the related influencing factors of inhalation compliance of seretide for chronic obstruc- tive pulmonary disease at stable stage. Methods 90 cases of patients with chronic obstructive pulmonary disease at sta- ble stage for inhalation of seretide in our hospital from January 2015 to June 2017 were selected, and the compliance was determined, and the differences in the related factors of patients of different compliances were surveyed by the self-made questionnaire. Results Of 90 cases, there were 41 cases with good compliance （45.569＂o, 41/90）, 49 cases with bad compliance （54.449＂o, 49/90）; and the Logistic regression analysis showed that the related factors： ~〉70 years old （0R=4.70, 95%CI： 2.33-22.05） , cognition deviation of chronic obstructive pulmonary disease （0R=3.88, 95%CI： 2.09-19.04）, seretide adverse reactions （0R=3.56, 95%CI： 1.58-18.23）, general medical relationship（OR=3.02, 95% CI： 1.23-17.23） Conclusion The age, cognition of chronic obstructive pulmonary disease, seretide adverse reactions, and medical relationship affects the compliance, and we should implement the corresponding measures to improve the compliance to the seretide.