儿童功能性消化不良的流行病学及药物治疗研究进展

Progress on the Epidemiology and Drug Therapy of Functional Dyspepsia in Children

功能性消化不良属上消化道功能障碍性疾病,是儿科常见病。因患儿常伴不同程度的恶心、呕吐、上腹疼痛、餐后饱腹感等临床症状,严重影响患儿的日常生活与学习,对其生活质量产生严重的负面影响。目前,治疗功能性消化不良的方法较多,包括西药治疗、中药治疗、中西医结合治疗等,然而尚未有任一种药物能够帮助患儿临床症状完全缓解。近年来,随着功能性影像学、神经胃肠病学、受体药物学、心理学的发展,临床对儿童功能性消化不良的认识已经进入了一个新阶段,其流行病学与药物治疗方案也有新发现与新进展。

Functional dyspepsia is is an upper gastrointestinal dystunction disease, which is a common pediatric disease. The children often have varying degrees of nausea, vonfiting, upper abdonfinm pain, postprandial satiety and other clinical symptoms, which severely affect children＇s daily life and learning, and it has serious negative impact on the quality of life. At present, there are many methods for treating functional dyspepsia, including western medicine treatment, traditional Chinese medicine treatment, and integrated treatment of traditional Chinese and western medicine. However, no one drug has yet been able to completely relieve clinical symptonls of children. In recent years, with the development of func- tional imaging, neurogastroentology, receptor pharmacology and psychology, clinical understanding of children＇s functional dyspepsia has entered a new stage, and its epidemiology and drug therapy program are also have new discoveries and developments.