移植肾动脉舒张期反向血流的临床意义

Clinical value of reversed diastolic flow in transplanted kidney

目的:评价移植肾动脉彩色多普勒超声检查中出现的舒张期反向血流(RDF)的临床意义。方法:对我院自2011年以来进行肾移植手术患者的临床资料进行回顾性研究,统计了所有出现RDF的病例,追踪记录其预后,并按照RDF发生时间和频谱形态进行分组。结果:42例移植肾患者出现了RDF,其原因包括排斥反应(24例)、急性肾小管坏死(7例)、肾静脉血栓(9例)、肾静脉受压(2例)。最终失肾率高达60%,仅3例患者肾功能恢复。结论:移植肾动脉出现RDF表明移植肾状态差,提示预后不良。但其发生时间及频谱形态与移植肾预后及病因无明显关联。

Objective：To estimate the significance of reversed diastolic flow（RDF）on Doppler ultrasonography in transplanted kidney.Method：A retrospective study involving all the renal-allograft recipients since 2011 in our hospital was done.All patients with RDF were counted and their prognosis was tracked.Those patients were grouped according to occurrence time and waveform morphology of RDF.Result：Forty-two patients with RDF were found.The causes were rejection（n=24）,acute tubular necrosis（n=7）,renal vein thrombosis（n=9）and oppressed renal vein（n=2）.As a result,60% of renal transplanted patients in this study lost their allografts.Only three allografts with RDF recovered their function eventually.Conclusion：RDF is a poor prognostic sign,which can indicate the bad situation of the allograft.However,neither the causes of RDF nor the prognosis of allograft had significant relationship with the waveform morphology or the occurrence time of RDF.