摘要
为改善麦角甾醇的溶解性,通过化学法在常温条件下制备硫辛酸麦角甾醇酯,并研究硫辛酸麦角甾醇酯在油中的抗氧化性。通过单因素试验,确定反应的最佳工艺条件为:以DMAP/EDC/Et_3N为催化剂,麦角甾醇浓度80 mmol/L,硫辛酸:麦角甾醇:DMAP:EDC:Et_3N摩尔比2. 0:1. 0:0. 2:1. 2:1. 5,溶剂二氯甲烷,反应温度25℃,反应时间20h;该条件下最终酯化率可达到91%以上。麦角甾醇硫辛酯在油中的溶解度约为麦角甾醇的2倍,抗氧化效果约为麦角甾醇的1. 5倍。
To improve the solubility of ergosterol,the ergosteryl lipoate was prepared by a chemical method under ambient temperature,and the antioxidation of ergosteryl lipoate in oil was studied. By single factor experiments,the optimum conditions for the synthesis of ergosteryl lipoate were obtained. The conversion could be achieved 91% in the following conditions： DMAP/EDC/Et_3N as the catalyst,80 mmol/L ergosterol,molar ratio of lipoic acid/ergosterol/DMAP/EDC/Et3N 2. 0 ：1. 0 ：0. 2：1. 2：1. 5,dichloromethane as the solvent,reaction temperature of 25℃,reaction time of 20 h. The solubility of ergosteryl lipoate in oil is about twice of ergosterol,and the antioxidant ability is about 1. 5 times of ergosterol.
作者
唐小卉
纪苏萍
夏雪
贾承胜
TANG Xiao-hui, JI Su-ping ,XIA Xue ,JIA Cheng-sheng(School of Food Science and Technology, Jiangnan University, Wuxi , Jiangsu 214122, China)
出处
《食品与机械》
CSCD
北大核心
2018年第8期129-134,共6页
Food and Machinery
基金
江苏省自然科学基金(编号:BK20161133)
江苏省研究生科研创新计划项目(编号:KYCX17_1463)
关键词
麦角甾醇
酯化
麦角甾醇酯
油溶性
抗氧化
ergosterol
esterification
ergosteryl lipoate
oil soluhility
antioxidation
