七项咽鼓管功能障碍症状评分量表的临床应用

Clinical application of seven-item Eustachian Tube Dysfunction Questionnaire

目的:探讨七项咽鼓管功能障碍症状评分量表(ETDQ-7)评估咽鼓管功能障碍治疗前后的临床价值。方法:前瞻性分析咽鼓管功能障碍患者50例,所有患者均于鼻内镜下咽鼓管吹张给予注射用糜蛋白酶4 000IU和地塞米松注射液5mg,1次/d,连续使用3~6d,同时应用盐酸氮卓斯汀鼻喷剂和布地奈德鼻喷剂,2喷/次,2次/d;口服欧龙马滴剂,3ml/次,3次/d。患者于治疗前及治疗结束后分别填写ETDQ-7。结合患者耳内镜检查、纯音听阈测试、声导抗测试、咽鼓管压力测定等结果综合评定疗效。结果:治疗后ETDQ-7评分为(15.6±7.1)分,显著高于治疗前(23.1±6.5)分,差异有统计学意义(P<0.05)。所有患者治疗后自觉耳闷胀感、耳鸣或不适感、听力下降等症状较前缓解,观察鼓膜像情况较治疗前改善,鼓室积液、鼓膜内陷等程度较前减轻,与ETDQ-7评分基本一致。结论:ETDQ-7在评估咽鼓管功能障碍治疗前后具有较好的临床价值,是一种可重复且有效的评估咽鼓管功能障碍的方法。

Objective：To investigate the clinical value of the seven-item Eustachian Tube Dysfunction Questionnaire（ETDQ-7）in evaluating Eustachian tube dysfunction before and after treatment.Method：A retrospective analysis of 50 patients with Eustachian tube dysfunction diagnosed.All the patients were given chymotrypsin 4000 IU and dexamethasone injection 5 mg by blowing through the Eustachian tube under nasal endoscopic guidance once daily for 3-6 consecutive days.At the same time,azelastine hydrochloride nasal spray and budesonide nasal spray were applied,2 sprays each time,2 times a day;oral Olongma drops,3 ml each time,3 times a day.ETDQ-7 was completed before and after treatment,and the results of ear endoscopy,pure tone audiometry,acoustic impedance test,and Eustachian tube function test were analyzed comprehensively.Result：The ETDQ-7 score（15.6±7.1）after treatment was significantly higher than that before treatment（23.1±6.5）points（P0.05）,and the difference was statistically significant.After treatment,all patients felt that aural fullness,tinnitus or discomfort,hearing loss and other symptoms were relieved.The tympanic membrane was observed to be better than before treatment.The tympanic effusion and tympanic membrane invagination were improved,which was in line with the change of ETDQ-7 score.Conclusion：ETDQ-7 has a good clinical value in the evaluation of Eustachian tube dysfunction before and after treatment.It is a reproducible and effective method for evaluating Eustachian tube dysfunction（ETD）.