止血方治疗围绝经期异常子宫出血肝肾阴虚证30例临床观察

Clinical Observation on Zhixue Prescription for 30 Cases of Abnormal Uterine Bleeding in Perimenopause with Liver-kidney Yin Deficiency Syndrome

目的:观察止血方治疗围绝经期异常子宫出血(AUB)肝肾阴虚证的临床疗效。方法:选取60例围绝经期AUB肝肾阴虚证患者作为研究对象,随机分为治疗组和对照组各30例。对照组予以葆宫止血颗粒治疗,治疗组予止血方治疗,2组均以服药14天为1疗程,共治疗3疗程,随访3月。对比分析2组治疗效果,观察2组治疗前后肝肾阴虚证证候积分的变化。结果:治疗后,治疗组肝肾阴虚证证候积分较治疗前降低,差异有统计学意义(P <0.05)。对照组治疗前后肝肾阴虚证证候积分比较,差异无统计学意义(P> 0.05)。治疗3疗程及随访3月,治疗组临床疗效均优于对照组,差异均有统计学意义(P <0.05)。结论:止血方治疗围绝经期AUB肝肾阴虚证效果优于葆宫止血颗粒。

Objective： To observe the clinical effect of Zhixue prescription for abnormal uterine bleeding（AUB） in perimenopause with liver-kidney yin deficiency syndrome. Methods： Selected 60 cases of patients with AUB in perimenopause with liver-kidney yin deficiency syndrome as study subjects and divided them into the control group and the treatment group randomly, 30 cases in each group. The control group received Baogong Zhixue granules for treatment,while the treatment group received Zhixue prescription for treatment. The two groups were treated for three courses, fourteen days being a course, and were followed up for three months.Compared and analyzed the clinical effect in the two groups, observed the syndrome scores of liver-kidney yin deficiency syndrome before and after treatment. Results：After treatment,the syndrome score of liver-kidney yin deficiency syndrome in the treatment group was decreased when compared with that before treatment,the difference being significant（P〈0.05）. No significant difference was found in the comparison of the syndrome score of liver-kidney yin deficiency syndrome in the control group before and after treatment（P〉0.05）. After treatment of three courses and follow-up of three months,the clinical effect in the treatment group was better than that in the control group, differences being significant（P〈0.05）. Conclusion： The effect of the therapy of Zhixue prescription for AUB in perimenopause with liver-kidney yin deficiency syndrome is better than that of Baogong Zhixue granules.