摘要
目的:观察针灸联合少腹逐瘀汤治疗原发性痛经(寒凝血瘀型)的临床疗效。方法:将50例患者随机分为2组各25例,观察组采取少腹逐瘀汤配合针灸进行治疗;对照组仅采用少腹逐瘀汤口服治疗;2组均以1个月经周期为1疗程,共治疗3疗程。于治疗前后及随访3月评估患者疼痛视觉模拟评分法(VAS)评分;检测患者治疗前后血清前列腺素2α(PGF2α)、前列腺素E2(PGE2),计算PGF2α/PGE2值;疗程结束统计2组临床疗效。结果:总有效率观察组为96.0%,对照组为88.0%,2组比较,差异无统计学意义(P> 0.05);治愈率观察组为80.0%,对照组为60.0%,2组比较,差异有统计学意义(P <0.05)。治疗后及随访3月,2组VAS评分均较治疗前明显改善(P <0.05),且治疗组VAS评分较对照组同时段改善更显著(P <0.05)。治疗后,2组血清PGF2α水平较治疗前降低(P <0.05),PGE2水平较治疗前升高(P <0.05);但上述指标2组间比较,差异均无统计学意义(P>0.05)。治疗后2组PGF2α/PGE2值比较,差异无统计学意义(P> 0.05)。结论:少腹逐瘀汤联合针灸治疗寒凝血瘀型原发性痛经患者可提高临床疗效,值得临床推广应用。
Objective:To observe the clinical effect of acupuncture and moxibustion combined with Shaofu Zhuyu tang for primary dysmenorrhea(cold-coagulation and blood-stasis type). Methods: Divided 50 cases of patients into two groups randomly, 25 cases in each group. The observation group was given Shaofu Zhuyu tang combined with acupuncture and moxibustion for treatment,while the control group was given Shaofu Zhuyu tang only. The treatment for both groups was 3 courses, one menstrual cycle as a course.Evaluated the score of visual analogue scale(VAS) before and after the treatment as well as after three months of follow-up,detected the prostaglandin 2α(PGF2α) and prostaglandin E2(PGE2) in serum before and after treatment, and calculated the number of PGF2α/PGE2. Counted the clinical effect in the two groups at the end of the treatment. Results:The total effective rate was 96.0% in the observation group and 88.0% in the control group,There being no significant difference(P〉0.05). During three months of follow-up after treatment,VAS scores in both groups were significantly improved when compared with those before treatment(P〈0.05),and the improvement of the VAS scores in the treatment group was more evident than that in the control group at the same time(P〉0.05). After treatment,PGF2α levels in serum in the two groups were decreased when compared with those before treatment(P〈0.05),and PGE2 levels were increased when compared with those before treatment(P〈0.05),but there was no significant difference between being found in the comparisons of the previous indexes(P〈0.05). After treatment,there was no significant difference being found in the comparisons of the number of PGF2α/PGE2 in the two groups(P〈0.05). Conclusion:The therapy of Shaofu Zhuyu tang combined with acupuncture and moxibustion for patients with primary dysmenorrhea of cold-coagulation and blood-stasis type can improve the clinical effect,and it is worthy of clinical application.
作者
杜文玲
周帆
何乐中
DU Wenling;ZHOU Fan;HE Lezhong
出处
《新中医》
CAS
2018年第10期153-155,共3页
New Chinese Medicine
关键词
原发性痛经
寒凝血瘀
少腹逐瘀汤
针灸疗法
Primary dysmenorrhea
Cold-coagulation and blood-stasis
Shaofu Zhuyu tang
Acupuncture and moxibus-tion therapy