大气托毒法联合古九针(立新七针)及中药倒模治疗聚合性痤疮疗效观察

Clinical Observation of Daqi Promoting Pus Discharge Method Combined with Nine Classical Needles(Lixi's Seven Needles) and Chinese Medicine Mold for Acne Conglobata

目的:观察大气托毒法联合古九针(立新七针)及中药倒模治疗聚合性痤疮的临床疗效。方法:将60例聚合性痤疮随机分为2组。治疗组给予大气托毒方加减联合古九针(立新七针)治疗;对照组予多西环素片连服1周,再用异维A酸软胶囊口服;2组均用本院自制中药搽剂,继而石膏倒膜;疗程均为12周。分别于治疗初始和治疗4、8、12周时观察和记录患者面颈胸肩背部皮损评分、皮损改善程度、不良反应;并于第16周时随访皮损反复的情况。结果:治疗4周、治疗8周、治疗12周,2组皮损情况比较,差异有统计学意义(P <0.05)。治疗4周后,治疗组总有效率50.00%,对照组为33.33%,经秩和检验,差异无统计学意义(P> 0.05)。治疗8周后,治疗组总有效率93.33%,对照组为60.00%,经秩和检验,差异有统计学意义(P <0.05)。治疗12周后,治疗组总有效率93.33%,对照组为83.33%,经秩和检验,差异有统计学意义(P <0.05)。2组第16周时随访,治疗组皮损反复25.00%,对照组40.00%,2组皮损反复率比较,差异无统计学意义(P> 0.05)。结论:大气托毒法联合古九针(立新七针)及中药倒模治疗聚合性痤疮具有起效更快,临床治愈率和有效率更高,皮损反复率更小,不良反应少的特点。

Objective：To observe the clinical effect of Daqi promoting pus discharge method combined with nine classical needles（Lixi＇s seven needles） and Chinese medicine mold for acne conglobata. Methods：Divided 60 cases of patients with acne conglobata into two groups randomly. The treatment group was treated with modified Daqi promoting pus discharge method combined with nine classical needles（Lixi＇s seven needles）,while the control group was given doxycycline tablets for one week and then treated with isotretinoin soft capsules. Both groups were given self-made Chinese medicine liniment first and plaster stone mold casting later. The course of the treatment was both 12 weeks. Observed and recorded the skin lesion scores of the face,neck,shoulder and back and skin lesions as well as adverse reactions at the beginning of treatment and 4 th,8 th and 12 th week of treatment respectively. Followed up the recurrent skin lesions at the 16 thweek. Results：After 4,8 and 12 weeks of treatment,compared the skin lesions in the two groups,difference was significant（P〈0.05）. After 4 weeks of treatment,the total effective rate was 50.00% in the treatment group and 33.33% in the control group, evaluated by rank sum test, difference being insignificant（P〉0.05）. After 8 weeks of treatment, the total effective rate was 93.33% in the treatment group and 60.00% in the control group,tested by rank sum test,difference being significant（P〈0.05）. After 12 weeks of treatment,the total effective rate was 93.33% in the treatment group and 83.33% in the control group,evaluated by rank sum test,difference being significant（P〈0.05）. Followed up the two groups at the 16 th week of treatment,the recurrent lesions were 25.00% in the treatment group and 40.00% the control group,compared the rate of skin recurrent lesions,difference being insignificant（P〈0.05）. Conclusion：Daqi promoting pus discharge method combined with nine classical needles（Lixi＇s seven needles） and Chinese medicine mold for acne conglobata is characterized by faster effect,higher clinical cure rate and effective rate and smaller recurrent skin lesions rate with less adverse reactions.