银杏蜜环口服液联合脑循环治疗仪治疗脑梗死后认知功能障碍

Ginko leaf extract and armillariella mellea powders oral solution combined with cerebral circulation therapeutic apparatus in the treatment of post cerebral infarction cognitive dysfunction

目的探讨银杏蜜环口服液联合脑循环治疗仪治疗脑梗死后认知功能障碍的临床疗效。方法选择我院脑梗死后认知功能障碍患者140例,随机分为观察组(n=70)和对照组(n=70),两组患者均给予多奈哌齐治疗(5 mg/次,一日1次),对照组采用脑循环治疗仪进行治疗(一日1次,每次治疗30 min),观察组在对照组基础上给予银杏蜜环口服液(10 ml/次,一日3次),连续治疗3个月。分别于治疗前和治疗结束后1周内对患者采用蒙特利尔认知功能评估(Mo CA)量表、韦克斯勒记忆量表(WMS)和日常生活活动能力(ADL)量表,比较治疗前后患者认知功能改变。结果与治疗前相比,两组治疗后Mo CA量表、WMS和ADL量表评分均升高(P<0.05);与对照组相比,观察组治疗后Mo CA量表、WMS和ADL量表评分更高(P<0.05)。结论银杏蜜环口服液联合脑循环治疗仪治疗脑梗死患者可以改善认知功能和ADL,促进患者康复,值得临床推广使用。

Objective To investigate the effect of Ginko leaf extract and armillariella mellea powders oral solution combined with cerebral circulation therapeutic apparatus in the treatment of post cerebral infarction cognitive dysfunction. Methods A total of 140 patients with post cerebral infarction cognitive dysfunction were randomly divided into observation group（n=70） and control group（n=70）. All patients were treated with donepezil（5 mg/time, once a day）, and given cerebral circulation therapeutic apparatus（30 minutes for each treatment, once a day）. The observation group was additionally given Ginko leaf extract and armillariella mellea powders oral solution（10 ml/time, three times a day） for 3 months. The Montreal cognitive function assessment（MoCA） scale, Wechsler memory scale（WMS） and activity of daily living（ADL） scale were used to compare the cognitive function changes before and after treatment. Results Compared with before treatment, the scores of the MoCA, WMS and ADL scale in two groups after treatment were increased（P〈0.05）. Compared with control group, the scores of the MoCA, WMS and ADL scale in observation group were higher（P〈0.05）. Conclusion Ginko leaf extract and armillariella mellea powders oral solution combined with cerebral circulation therapeutic apparatus can improve cognitive function and activity of daily living in the patients with cerebral infarction, and promotepatients＇ recovery.