高压氧治疗颅脑损伤的效果观察

Effects of hyperbaric oxygen therapy on craniocerebral injury

目的探讨高压氧治疗颅脑损伤的临床疗效。方法选取2014年6月至2017年6月120例重度、中度颅脑损伤患者作为研究对象,回顾性分析其临床资料,按照随机数字表法随机分为观察组与对照组,每组60例。两组患者均给予常规治疗,观察组患者联合高压氧治疗,比较两组患者的临床疗效。结果入院时两组患者格拉斯哥昏迷评分(GCS)比较差异未见统计学意义(P> 0. 05);高压氧治疗第10、20、30天,观察组GCS评分均优于对照组,差异有统计学意义(P <0. 05)。观察组治疗总有效率为61. 7%,高于对照组的43. 3%,差异有统计学意义(P <0. 05)。结论高压氧治疗颅脑损伤患者具有显著的临床疗效,能够提高GCS评分,改善预后。

Objective To investigate the clinical effects of hyperbaric oxygen therapy on craniocerebral injury. Methods A total of 120 patients with severe and moderate craniocerebral injury from June 2014 to June 2017 were selected as the subjects, their clinical data was retrospectively analyzed, and they were randomly divided into the observation group and the control group according to the random number table method, with 60 cases in each group. The patients in the control group were given conventional treatment, while the patients in the observation group were treated by the conventional treatment combined with hyperbaric oxygen treatment. The clinical effects of the two groups were compared. Results There was no significant difference in GCS score between the two groups at admission （P 〉 0. 05）. The GCS scores of the observation group were better than those of the control group on the 10 th, 20 th and 30 th day after the hyperbaric oxygen treatment （ P 〈 0. 05 ）. The total effective rate of the observation group was 61.7%, which was higher than that of the control group （43.3%）, and the difference was significant （P 〈 0. 05 ）. Conclusions Hyperbaric oxygen has obvious clinical effects on patients with craniocerebral injury, and which can improve the GCS score and prognosis.