药物洗脱球囊与药物洗脱支架治疗冠状动脉支架内再狭窄的效果比较

Comparison on effects of drug-eluting balloon and drug-eluting stent on coronary in-stent restenosis

目的 探讨药物洗脱球囊（DEB）与药物洗脱支架（DES）治疗冠状动脉支架内再狭窄（ISR）的安全性和有效性.方法 选取2016年1月至2017年2月郑州市第七人民医院心内科收治的冠状动脉支架内再狭窄患者83例,根据治疗方法分为紫杉醇药物洗脱球囊组（DEB组）39例和紫杉醇药物洗脱支架组（DES组）44例.比较两组患者的心血管不良事件发生情况、ISR发生例数、最小管腔直径及管腔狭窄率.结果 DEB组和DES组心血管不良事件发生情况、ISR发生例数、最小管腔直径、管腔狭窄率比较,差异未见统计学意义（P〉0.05）.结论 DEB治疗ISR安全可行,疗效不差于DES再置入.

Objective To investigate the safety and efficacy of drug eluting balloon （ DEB） and drug-eluting stent （ DES ） on coronary in-stent restenosis （ ISR ） .Methods Eighty-three patients with coronary ISR admitted to the Department of Cardiology of the Seventh People ＇s Hospital of Zhengzhou from January 2016 to February 2017 were selected .And they were divided into paclitaxel-eluting balloon group （ DEB group , n=39 ） and paclitaxel-eluting stent group （ DES group , n=44 ） according to the treatment methods . The incidence of adverse cardiovascular events , the number of ISR cases , the minimum lumen diameter and the lumen stenosis rate of the two groups were compared .Results There was no significant difference in incidence of adverse cardiovascular events , the number of ISR cases , the minimum lumen diameter or the lumen stenosis rate between DEB group and DES group （ P〉0.05 ） . Conclusions DEB in treatment of ISR is safe and feasible , and the curative effect is not inferior to DES re-implantation .