摘要
目的:探索克罗恩病(Crohn’sdisease,CD)发病的危险因素。方法:采用1:1配对病例对照研究。采用t检验、χ2检验、单因素、多因素条件logistic回归分析CD与对照组的相关危险因素。结果:单因素分析显示西餐、蔬菜水果、饮酒、居住条件与CD发病有关(P<0.20)。多因素分析显示仅西餐为CD发病的危险因素(P=0.015,OR=12.729,95%CI 1.656～97.855)。结论:进食西餐可能为贵州地区CD发病的危险因素。
Objective： To explore the potential risk factors in the development of Crohn＇s disease（CD）. Methods： A matched case-control（1：1） study was designed. T test, Chi-square test, conditional logistic regression was used to comparatively analyze the potential risk factors between CD patients and the controls. Results： Univariate analysis showed that western food, fruits and vegetables, alcohol drinking, and housing condition were statistically correlated with CD（P〈0.20）. However, multivariate logistic regression analysis indicated that western food was only risk factor of CD in Guizhou population（P=0.015, OR=12.729, 95%CI 1.656–97.855）. Conclusion： Western food may be a risk factor in the pathogenesis of CD in Guizhou population.
作者
崔德军
杨柳婵
杨小兰
韩然
袁文强
张曼曼
CUI Dejun;YANG Liuchan;YANG Xiaolan;HAN Ran;YUAN Wenqiang;ZHANG Manman(Department of Gastroenterology,Guizhou Provincial People＇s Hospital,Guiyang 550002;The Medical College of Guizhou University,Guiyang 5.50025;Department of Gastroenterology,The Affiliated People＇s Hospital of Guizhou Medical University,Guiyang 550002,China)
出处
《临床与病理杂志》
2018年第9期1913-1916,共4页
Journal of Clinical and Pathological Research
基金
贵州省卫生和计划生育委员会科学技术基金(gzwjkj2016-1-004)
贵州省人民医院博士基金[GZSYBS(2017)09]
北京医卫健康公益基金会医学科学研究基金(YWJKJJHKYJJ-B184053)~~
关键词
克罗恩病
炎症性肠病
危险因素
病例对照研究
Crohn＇s disease
inflammatory bowel disease
risk factor
case-control study
