胸腔镜肺叶切除和肺段切除治疗ⅠA期非小细胞肺癌的疗效比较

Comparison of Thoracoscopic Lobectomy and Segmentectomy for ⅠA Non-small Cell Lung Cancer

目的比较胸腔镜肺叶切除和肺段切除在ⅠA期非小细胞肺癌患者中的治疗效果。方法回顾性分析2012年5月～2014年5月在我院行胸腔镜手术的76例ⅠA期NSCLC患者资料,按手术方式分为两组,观察组50例行肺叶切除术,对照组26例行肺段切除术。比较两组患者的手术时间、术中出血量、留置引流管时间、住院天数、并发症发生率、随访3年后复发率及死亡率。结果观察组手术时间为(118.26±30.76)min,短于对照组的(155.51±21.91)min,差异具有统计学意义(P<0.05)。两组患者术中出血量、留置引流管时间、住院天数、并发症发生率、随访3年后复发率和死亡率比较,差异无统计学意义(P>0.05)。结论ⅠA期NSCLC患者中肺段切除和肺叶切除治疗效果相似,而且肺段切除术能够保留更多的肺功能,有利于患者恢复。

Objective To compare the therapeutic effects of thoracoscopic lobectomy and segmentectomy in patients with stage IA non-small cell lung cancer. Methods A retrospective analysis of 76 patients with stage IA NSCLC who underwent thoracoscopic surgery from May 2012 to May 2014 was divided into two groups according to the operation. 50 patients underwent lobectomy in the observation group and 26 patients in the control group underwent segmental resection. The operation time, intraoperative blood loss, indwelling drainage tube time, length of hospital stay, complication rate, recurrence rate and mortality after 3 years of follow-up were compared between the two groups. Results The operation time of the observation group was （118.26±30.76） min, which was shorter than that of the control group （155.51±21.91） min,the difference was statistically significant （P〈0.05）. There were no significant differences in intraoperative blood loss, indwelling drainage time, length of hospital stay, complication rate, and recurrence rate and mortality after 3 years of follow-up between the two groups （P〉0.05）. Conclusion The treatment of segmental resection and lobectomy in patients with stage IA NSCLC is similar,and segmentectomy can preserve more lung function and facilitate recovery.