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沙利度胺治疗小肠血管发育不良并发出血的疗效评价

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摘要 目的探究沙利度胺治疗小肠血管发育不良并发出血的有效性。方法选取2015年1月1日至2017年6月30日该院收治的小肠血管发育不良并发出血患者42例作为观察对象,所有患者口服沙利度胺,治疗16周,随访36周,观察治疗前后各项指标的变化。结果所有患者经治疗后出血频率减少,每次出血时间缩短,头晕、乏力症状均得到改善,血红蛋白水平升高,与治疗前比较,差异均有统计学意义(P<0.05)。治疗过程中有5例患者出现不良反应,经治疗后症状缓解,治疗期间未停药。结论小肠血管发育不良并发出血的治疗中,沙利度胺疗效明确,药物安全性高。
出处 《现代医药卫生》 2018年第21期3346-3348,共3页 Journal of Modern Medicine & Health
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  • 1戈之铮,徐春红,刘文忠,陈海英,高云杰,胡运彪,萧树东.反应停在治疗血管发育不良所致消化道出血中的作用——附7例疗效观察[J].胃肠病学,2006,11(1):8-11. 被引量:10
  • 2Stephanos Karagiannis,Spyros Goulas,Georgios Kosmadakis,Petros Galanis,Dimitrios Arvanitis,John Boletis,Evangelos Georgiou,Christos Mavrogiannis.Wireless capsule endoscopy in the investigation of patients with chronic renal failure and obscure gastrointestinal bleeding (preliminary data)[J].World Journal of Gastroenterology,2006,12(32):5182-5185. 被引量:8
  • 3Bounds BC, Kelsey PB. Lower gastrointestinal bleeding. Gastrointest Endosc Clin N Am,2007,17:273-288.
  • 4Szilagyi A, Ghali MP. Pharmacological therapy of vascular malformations of the gastrointestinal tract. Can J Gastroenterol, 2006,20:171-178.
  • 5Bauditz J, Schachschal G, Wedel S, et al. Thalidomide for treatment of severe intestinal bleeding. Gut,2004, 53:609-612.
  • 6Junquera F, Saperas E, de Torres I, et al. Increased expression of angiogenic factors in human colonic angiodysplasia. Am J Gastroenterol, 1999,94 : 1070-1076.
  • 7Maier SK, Hammond JM. Role of lenalidomide in the treatment of multiple myeloma and myelodysplastic syndrome. Ann Pharmacother,2006 ,40 :286-289.
  • 8Heidt J, Langers AM, van der Meer FJ, et al. Thalidomide as treatment for digestive tract angiodysplasias. Neth J Med, 2006, 64:425-428.
  • 9Harris AL. Hypoxia-a key regulatory factor in tumour growth. Nat Rev Cancer,2002, 2:38-47.
  • 10Takahashi A, Sasaki H, Kim SJ, et al. Markedly increased amounts of messenger RNAs for vascular endothelial growth factor and placenta growth factor in renal cell carcinoma associated with angiogenesis. Cancer Res, 1994,54:4233-4237.

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