慢性肺源性心脏病患者超敏C反应蛋白及纤维蛋白原表达及临床意义

Expression of Hypersensitive C-reactive Protein and Fibrinogen in Patients with Chronic Cor Pulmonale and its Clinical Significance

目的:检测慢性肺源性心脏病急性加重期和稳定期患者血清超敏C反应蛋白(hs-CRP)和纤维蛋白原(Fib)含量的变化,并分析其临床意义。方法:选择慢性肺心病缓解期患者34例(对照组)和急性加重期患者36例(观察组)测定血清hs-CRP及Fib。结果:观察组患者血清hs-CRP及Fib水平均高于对照组,差异有统计学意义(P<0.005)。结论:hs-CRP及Fib的检测对慢性肺源性心脏病急性加重期的病情评估和治疗具有一定的指导意义。

Objective： To analyze the clinical significance through investigating the level of hypersensitiveC-reactive protein and fibrinogen in the patients with pulmonary heart disease. Methods： Hypersensitive C-reactiveprotein and fibrinogen was measured in 36 cases with chronic pulmonary heart disease in the acute exacerbation（observation group）, 34 cases with chronic pulmonary heart disease in the clinical remission （control group）. Results：The levels of hypersensitive C-reactive protein and fibrinogen in the patients with pulmonary heart disease in theacute exacerbation was higher than that in the patients with clinical remission. Conclusion： The test of hs-CRPand Fib has certain guiding significance for the assessment and treatment of chronic pulmonary heart disease in theacute exacerbation.