子宫内膜异位症合并不孕者腹腔镜治疗后影响妊娠率相关非药物危险因素

Study on the Non-drug Risk Factors Associated with Pregnancy Rate in Patients with Endometriosis Associated Infertility after Laparoscopic Surgery Treatment

目的:通过单因素和多因素分析筛选出与子宫内膜异位症合并不孕者腹腔镜治疗后妊娠率相关的危险因素,为临床治疗提供依据。方法:收集行腹腔镜手术治疗的128例内异症合并不孕患者的临床资料,分析影响术后妊娠率的相关非药物影响因素。结果:128例患者中,腹腔镜术后24个月的累积受孕率为39. 84%,其中术后12个月内的受孕率为27. 34%,术后13～24个月的受孕率12. 50%,差异具有统计学意义(P <0. 05)。单因素分析结果显示,不同年龄、不孕类型、不孕年限、输卵管功能等因素的腹腔镜术后妊娠率比较差异均有统计学意义(P <0. 05)。Logistic回归分析结果显示影响内异症患者腹腔镜术后妊娠率的相关因素为年龄、不孕类型、不孕年限和输卵管功能。结论:对于行腹腔镜手术治疗的内异症合并不孕患者,应重视年龄、不孕类型、不孕年限、输卵管功能对妊娠成功率的影响。

To explore the non drug factors associated with pregnancy rate in patients with endometriosis associated infertility after laparoscopic surgery through univariate and nmhivariate analysis screened out to provide basis for clinical treatment. Methods： 128 patients with endometriosis associated infertility after laparoscopic surgery in our hospital were prospectively collected for risk factors of pregnancy rate and analyzed. Results：The overall postoperative pregnancy rate within 24 months was 39.84%. The postoperative pregnancy rate was 27.34% and 12.50% in the first and the second year respectively. There were statistically significant differences among the two groups （P 〈 0.05 ）. The differences of postoperative pregnancy rate in the elements of age, type of infertility, duration of infertility, tubal func tion were all statistically significant（P 〈 0.05 ）. Logistic regression analysis showed that risk factors of pregnancy rate ininfertility and tubal function. Conclusions：For patients with en pic smgery included age, type of infertility, duration of dometriosis complicated with infertility undergoing laparoscopic surgery, it is essential to evaluate patients＇comprehensive situation, the influence of age, type of infertility, duration of infertility and tubal function on the success rate of pregnancy.