混合型过敏原阳性喘息性支气管炎儿童的免疫功能被引量：3

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摘要目的:观察分析食入、吸入、混合型过敏原阳性喘息性支气管炎儿童的免疫功能。方法:随机选取88例吸入性过敏原阳性患儿为吸入组,107例食入性过敏原阳性患儿为食入组,混合组60例。健康组340例。研究淋巴细胞亚群、体液的免疫水平、血清总Ig E和各淋巴细胞亚群之间的相关性。结果:吸入组、食入组、混合组患者血清CD4+Th17、CD4+CD25+Treg、Ig G水平高于健康对照组,且混合组患者CD4+Th17、CD4+CD25+Treg、Ig G水平高于吸入组及食入组,以上差异均有统计学意义(P <0. 05);喘息性支气管炎患儿血清总Ig E分别与CD3+CIN+T、CIN+/CD8+T和CD3 CDl9+CD23+B淋巴细胞亚群及CD3一CDl6+CD56+NK细胞相关。结论:吸入性过敏原致敏更易引起喘息性支气管炎患儿调节性T淋巴细胞的比例或功能,包含CD4+/CD8+的平衡失效及CD3+CD4+CD25+的降低等,从而影响体液免疫功能。

作者王雪华

机构地区郑州市中原区妇幼保健所

出处《山西职工医学院学报》 CAS 2018年第5期53-55,共3页 Journal of Shanxi Medical College for Continuing Education

关键词过敏原阳性喘息性支气管炎儿童免疫功能

分类号 R725.6 [医药卫生—儿科]

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