血清TPO-Ab、TSH、TGA检测在孕妇甲状腺疾病筛查中的意义

Significance of Detection of Serum TPO-Ab, TSH and TGA in Screening Thyroid Diseases in Pregnant Women

目的探究血清TPO-Ab、TSH、TGA检测在孕妇甲状腺疾病筛查中的意义。方法选择2017年1—12月我院甲状腺结节100例孕妇并设为观察组,选择同时期我院健康孕妇100例作为对照组,比较两组血清TPO-Ab、TSH、TGA水平。结果观察组血清TPOAb(42.0±5.0)IU/ml、TSH(3.9±0.5)μIU/ml、TGA(21.5±4.4)IU/ml,高于对照组,组间比较,差异具有统计学意义(P <0.05)。观察组血清TPO-Ab阳性率81.0%,TSH阳性率77.0%,TGA阳性率88.0%,高于对照组,组间比较,差异具有统计学意义(P <0.05)。结论血清TPO-Ab、TSH、TGA检测在孕妇甲状腺疾病筛查中的意义显著。

Objective To explore the significance of detection of serum TPO-Ab, TSH and TGA in screening thyroid diseases in pregnant women. Methods From January to December 2017, 100 pregnant women with thyroid nodules in our hospital were selected as the observation group. 100 healthy pregnant women in our hospital were selected as control group. The serum levels of TPO-Ab, TSH and TGA were compared between the two groups. Results The levels of serum TPO-Ab （42.0±5.0） IU/ml, TSH （3.9±0.5） μIU/ml and TGA （21.5±4.4） IU/ml in the observation group were higher than those in the control group, and the difference was statistically signifcant （P〈0.05）.The positive rate of serum TPO-Ab, TSH and TGA in the observation group was 81.0%, 77.0% and 88.0%, which were higher than that in the control group. The difference was statistically signifcant （P 〈 0.05）. Conclusion The detection of serum TPO-Ab, TSH and TGA is signifcant in screening thyroid diseases in pregnant women.