摘要
在BF_3·OEt_2的催化作用下, N-苄基-2-(2-羟甲基苯基氨基)乙酰胺与硝基苯甲醛反应合成了1-酰胺基苄基-2-芳基-3,1-苯并噁嗪。研究了催化剂对反应的影响,实验结果表明BF_3·OEt_2比TMSCl, pTsOH, ZnCl_2和FeCl_3对反应的催化活性高。
Using BF3·OEt2 as catalyst, N-benzyl-2-（2-hydroxymethylphenylamino）acetamide was reacted with nitrobenzaldehyde to obtain 1-amidobenzyl-2-aryl-3,1-benzoxazines. The effects of catalyst on the reaction were studied and the experimental results showed that BF3·OEt2 was of better catalytic activity than catalysts including TMSCl, p-TsOH, ZnCl2 and FeCl3.
作者
汪明
唐子龙
王恋
唐瑞仁
WANG Ming;TANG Zi-long;WANG Lian;TANG Rui-ren(Key Laboratory of Theoretical Organic Chemistry and Functional Molecule of Ministry of Education,Hunan University of Science and Technology,Xiangtan 411201,China;School of Chemistry and Chemical Engineering,Hunan University of Science and Technology,Xiangtan 411201,China;School of Chemistry and Chemical Engineering,Cental South University,Changsha 410085,China)
出处
《精细化工中间体》
CAS
2018年第4期16-18,59,共4页
Fine Chemical Intermediates
基金
国家自然科学基金(21877034)
湖南省教育厅项目(17A066)
理论有机化学与功能分子教育部重点实验室开放基金(LKF1603)
