面部寻常狼疮50年继发低分化鳞状细胞癌

Low-differentiated squamous cell carcinoma arises from lupus vulgaris

报告1例寻常狼疮继发低分化鳞状细胞癌。患者女,79岁。左侧面部及颈部红斑及结节50年,溃疡2年。皮肤科检查:左侧面、颈部及下颌部弥漫暗红色结节及斑块,其上可见溃疡。皮损组织病理检查:真皮内肿瘤细胞团块形成,细胞异形性明显,偶见角化不良细胞,未见角珠,真皮内可见结核样肉芽肿结构。诊断:寻常狼疮继发低分化鳞状细胞癌。

A case of lupus vulgaris complicated with low-differentiated squamous cell carcinoma is reported. A 79-year-old female presented with erythema and nodules on the left cheek and neck for fifty years, and ulcers for two years. Physical examination showed diffuse dark red nodules and plaques with visible ulcers on the left side of the face, neck and jaw. Histopathological examination of nodular lesion revealed granuloma in the dermis, while the ulcer lesion revealed masses of tumor cells in the dermis. Atypical cells and parakeratosis were evident. Tuberculoid granuloma was also seen in the dermis. The diagnosis of low differentiated squamous cell carcinoma arising from lupus vulgaris was confirmed.