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大剂量辛伐他汀强化治疗对缺血性脑血管病患者血脂水平及脑血管储备能力的影响分析 被引量:5

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摘要 目的:分析及探索缺血性脑血管病患者采用大剂量辛伐他汀治疗对其血脂与脑血管储备能力造成的影响。方法:选择缺血性脑血管病的80例患者,随机分成两组:参照组共有40例,在常规治疗基础上给予辛伐他汀常规剂量(20 mg/次,1次/d)治疗;观察组共有40例,在常规治疗基础上给予辛伐他汀大剂量(40 mg/次,1次/d)强化治疗。观察治疗前、后两组患者的血脂指标与脑血管储备能力变化。结果:观察组治疗后的总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)指标均显著低于治疗前,且明显低于参照组,高密度脂蛋白胆固醇(HDL-C)显著高于治疗前,且高于参照组,差异均有统计学意义(P <0. 05);观察组治疗后的屏气指数(BHI)、脑血管反应性(CVR)均显著高于治疗前,且高于参照组,差异均有统计学意义(P <0. 05)。结论:缺血性脑血管病患者采用大剂量辛伐他汀治疗能够有效改善其血脂水平与脑血管储备能力,值得广泛推广。
作者 李凯 李静
机构地区 中卫市人民医院
出处 《吉林医学》 CAS 2018年第11期2090-2091,共2页 Jilin Medical Journal
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