石墨烯量子点的抗菌性能及其在口腔医学中的应用前景

The antimicrobial activity and application of graphene quantum dots in oral medicine

细菌耐药问题日益严峻,如何能快速高效地检测和抑制耐药菌成为治疗口腔细菌感染的关键因素。作为石墨烯家族的一员,石墨烯量子点因其低分子量、高比表面积、良好的生物相容性、抗菌性以及特殊的可调节光致发光性能,可以作为新型抗菌材料、药物载体、光敏材料应用于口腔抗菌领域。本文就其合成方法、一般特性及在口腔医学中的应用作一综述。

The abuse of antibiotics has been increasing bacterial resistance, which means there is a need to develop methods for the efficient detection and effective treatment of multiresistant bacterial infections. As one of graphene-based materials, graphene quantum dots （GQDs） have distinct mechanical, electrical, and optical properties, including a small size, a large surface area-to-volume ratio, biocompatibility, antimicrobial activity and tunable photoluminescence. Therefore, GQDs are expected to be widely used as antimicrobial materials, drug delivery carriers and photosensitizers in antibacterial applications. In this review, we focus on their synthesis, characteristics and antimicrobial applications in oral medicine.