微生物与肿瘤免疫关系的研究进展

Research progress in relationship between microbes and tumor immunity

微生物与肿瘤的发生发展密切相关，微生物可通过免疫系统，影响肿瘤的发生发展和转移。本文从肿瘤发展过程中，微生物与巨噬细胞、T细胞、骨髓来源的抑制性细胞和其他免疫细胞的相互作用的关系做一综述。并总结微生物影响的抗肿瘤免疫治疗，提高人们对微生物影响肿瘤机制的全面认识，为肿瘤的预防、免疫治疗新疗法提供参考。

Microbes are closely associated with tumor development. The interactions between mi-crobes and immune system contribute to tumor progression and metastasis. This review focused on the inter-actions between microbes and immune cells （macrophages, T cells, myeloid-derived suppressor cells and other immune cells） in the course of tumor growth, and summarized the roles of microbes in tumor immuno-therapies, aiming to improve the overall understanding of the mechanisms for microbes affecting tumors, and provide ideas for tumor prevention and future immunotherapies.