多层螺旋CT肺动脉成像中对比剂剂量使用固定值的可行性研究

Comparison Between Fixed Dose of Contrast Medium and Variable Dose By Weight in Pulmonary Angiography By MultiSlice Computed Tomography

目的探讨肺动脉CT成像中对比剂用量使用固定值的可行性。方法肺动脉成像患者分为两组,试验组(A组):对比剂用量使用固定值(370 mg I/ml,35 ml);对照组(B组):对比剂用量按照0.7 ml/kg体重(370 mg I/ml)计算。分别测量A组与B组的肺动脉主干、上腔静脉及左心房的平均CT值,分析两组数据差异有无统计学意义。结果 A、B两组肺动脉主干、左心房平均CT值差异无统计学意义,上腔静脉CT平均值有显著性差异,B组大于A组。结论肺动脉CT成像中对比剂用量使用固定值是可行的。

Objective To evaluate the feasibility of fixed dose of contrast medium in pulmonary angiography by using multislice computed tomography( MSCT). Methods Consecutive patients scheduled for pulmonary angiography were allocated into intervention arm( group A) and control arm( group B) by the method of random number. Fixed dose of contrast medium in group A was 35 ml,whereas that in group B was generated by 0. 7ml / kg. Computerized tomography value( CT value) of main pulmonary artery( MPA),superior vena cava,and left atrium were measured,and then compared between groups. Results No statistical difference of CT value at MPA and left atrium between groups were demonstrated,however,statistical difference of CT value at superior vena cava between groups were identified( Group B > Group A,P value < 0. 05). Conclusion It is feasible and applicable to use fixed dose of contrast medium in pulmonary angiography by MSCT.