焦作地区乙肝六项模式在各个年龄组的分布及结果分析

Investigation of 6 Modes of HBV

目的 :探讨乙肝六项模式在各个年龄组的分布比例及同组和各组之间含HBsAg阳性模式阳性率差异。方法 :采用ELISA试剂盒对 3731例住院及门诊患者进行乙肝六项检测。结果 :全阴性与单独第二项阳性模式所占比例 ,0～ 7岁组 ,>5 6岁以上组 ,>2 6～ 5 5岁组 >8～ 2 5岁组 ,分别为 83.2 %、73.8%、6 2 .7%、6 2 .5 % ;男女含HBsAg阳性模式阳性率比较 ,0～ 7岁组没有显著性差异 (χ2 =0 .0 8,P >0 .75 )、8～ 2 5岁组有显著性差异 (χ2 =4.39,P <0 .0 5 )、2 6～ 5 5岁组有极显著性差异 (χ2 =10 .3,P <0 .0 0 5 )、5 6岁以上组没有显著性差异 (χ2 =2 .77,P >0 .0 5 ) ;各组之间HBsAg阳性模式阳性率有极显著性差异 (χ2 =36 .98,P <0 .0 0 5 )。结论 :8～ 2 5岁组、2 6～ 5 5岁组乙肝患病率较高 ,应间隔 3～ 5年加强乙肝疫苗的注射、并注意养成良好的卫生习惯 。

Objective:To study distribution of 6 modes of HBV among several age-groups and difference of positive HBsAg rate between men and women in same group and difference of positive HBsAg rate between several age groups. Methods:6 modes of HBV were detected by ELISA in a series of 3731 patients.Results:The rates of all negative but Anti-HBsAg were 83.2%?73.8%,62.7%,and 62.5%,resectively in 0～7 years old group,over 56 years group,26～55 years group, and 8～25 years old group. There was no significant difference of positive rate of HBsAg between men and women of 0～7 years old group(χ 2= 0.08,P>0.75) and the same result as in over 56 years old group(χ 2=2.77,P>0.05). There was a significant difference of positive rate of HBsAg between men and women both in 8～25 years old group(χ 2= 4.39,P<0.05)and in 26～55 years old group (χ 2=10.3,P<0.005).Again,positive HBsAg rate was significant difference between several age-groups (χ 2=36.98,P<0.005).Conclusion:Prevalence rate of HBV is higher in 8～25 years old group and 26～55 years old group,so vaccine of HBV should be administrated in every 3～5 years.