摘要
目的:探讨肾上腺节细胞神经瘤(AGN)的临床诊治特点及预后。方法:回顾性分析2006年1月~2018年3月我院收治的经手术病理证实的11例AGN患者的临床及随访资料。其中男5例,女6例;年龄18~61岁,平均37.7岁;肿瘤长径4.5~12.0cm,平均8.8cm。所有患者均行手术切除肿瘤,腹腔镜手术6例,开放手术5例。结果:全部病例均成功完成手术,术中1例出现血压剧烈波动,1例出现胸膜损伤,其余病例术中生命体征平稳,围手术期无特殊并发症。全部病例术后病理均诊断为AGN,无合并其他肿瘤成分。全部病例均获得随访,随访1~147个月,未见肿瘤复发、转移及新发代谢紊乱。结论:AGN发病率低,多数无内分泌功能,影像学特征有助于诊断,病理检查能明确诊断,生物学行为呈惰性,手术切除肿瘤是主要的治疗方式,预后良好。
Objective:To investigate the clinical characteristics and prognosis of adrenal ganglioneuroma.Method:We retrospectively analyzed the clinical and follow-up data of 11 patients with adrenal ganglioneuroma confirmed by postoperative pathological diagnosis from January 2006 to March 2018.There were 5 male and 6 female patients.Their mean age was 37.7 years old(range,18-61 years old).The mean tumor maximum diameter was 8.8 cm(range,4.5-12.0 cm).All patients underwent tumor resection surgery,including 6 laparoscopic surgeries and 5 open surgeries.Result:All procedures were performed successfully.One case with severe blood pressure fluctuation and another one case with pleura injury during operation were observed.All cases were pathologically diagnosed with adrenal ganglioneuroma,without other tumor components.No recurrence,metastasis or newly-emerged hormone disorder was observed during the follow-up period of 1-147 months.Conclusion:Adrenal ganglioneuroma,which has indolent hormone activity and behavior,is a rare tumor with favorable prognosis.Imaging feature contributes to diagnosis,while definitive diagnosis relies on pathological examination.Tumor resection surgery is the major therapy strategy.
作者
柯炳虎
刘银华
丁可珂
张振兴
卓栋
KE Binghu1,LIU Yinhua2,DING Keke1,ZHANG Zhenxing1,ZHUO Dong1(1.Department of Urology,Yijishan Hospital,Wannan Medical College,Wuhu, Anhui, 241001, China;2.Department of Pathology,Yijishan Hospital,Wannan Medical Colleg)
出处
《临床泌尿外科杂志》
2018年第10期793-796,共4页
Journal of Clinical Urology
关键词
肾上腺肿瘤
节细胞神经瘤
诊断
治疗
预后
adrenal gland neoplasms
ganglioneuroma
diagnosis
therapy
prognosis