电切术与电灼术治疗女性腺性膀胱炎的效果分析

Efficacy comparison of electro-resection and electro-fulguration for cystitis glandularis in female

目的探讨经尿道电切术与电灼术治疗女性腺性膀胱炎的疗效差异。方法选取住院治疗的女性腺性膀胱炎患者作为观察对象,其中42例行经尿道电灼术治疗(对照组),70例行经尿道电切术治疗(观察组),比较两组患者术后随访情况及疗效的差异。结果两组在手术时间、术中出血量、住院时间、留置尿管时间的比较中,差异无统计学意义(P> 0. 05)。两组术后24 h排尿次数及尿急次数较术前均下降(P <0. 05),其中观察组较对照组术后24 h排尿次数及尿急次数更低(P <0. 05)。两组患者术后总有效率无明显统计学差异(P> 0. 05)。但观察组患者术后治愈率显著高于对照组(P <0. 05)。电灼组患者术后1个月内症状缓解率较电切组缓解率高,但电切组术后半年症状总缓解率较电灼组高(P <0. 05)。两组患者术前Survivin、P53水平比较无显著差异,各组术后阳性率较术前均下降(P <0. 05),其中观察组较对照组术后Survivin、P53水平更低(P <0. 05)。结论对于女性腺性膀胱炎而言,采取经尿道电切术治疗效果更好,值得临床上进一步推广。

Objective To investigate the difference of curative effect between electro-resection and electrofulguration on female cystitis glandularis. Methods Female glandular cystitis patients who were hospitalized in Suzhou Jiulong Hospital were selected, including 42 patients undergoing transurethral electro-fulguration （control group） and 70 patients undergoing transurethral electro-resection （observation group）. Postoperative follow-up data and differences in efficacy were compared. Results There were no significant differences in the operation time, intraoperative blood loss, hospital stay, and indwelling catheter time between the two groups （ P 〉 0.05 ）. The number of urination and urinary urgency at 24 h after operation were lower than those before operation （ P 〈 0.05 ）, and the number of urination and urinary urgency were lower in the observation group than those in the control group at 24 h after operation （ P 〈 0.05 ）. There was no significant difference in the total effective rate between the two groups （ P 〉 0. 05 ）. However, the postoperative cure rate of the observation group was significantly higher than that of the control group （ P 〈 0.05 ）. In the electro-fulguration group, the symptom remission rate was higher than that in the electro-resection group within 1 month after surgery. However, the total remission rate of the resection group was higher in the electro-fulguration group （P 〈 0.05 ）. There were no significant differences in the levels of Survivin and P53 between the two groups before operation. The postoperative positive rate in each group was lower than that before surgery （P 〈 0.05）. The levels of Survivin and P53 in the observation group were lower than those in the control group （ P 〈 0.05 ）. Conclusion For female cystitis glandularis, transurethral electro-resection is better and worthy of further clinical promotion.