临床药师参与1例早产儿嗜麦芽窄食单胞菌感染抗菌药物治疗

Antibacterial Therapy for A Case of Premature Infant Infected by Stenotrophomonas Maltophilia Participated by Clinical Pharmacists

目的:探讨临床药师参与特殊人群多重耐药菌抗菌药物治疗的意义。方法:针对1例早产儿嗜麦芽窄食单胞菌感染,临床药师运用专业知识参与抗菌药物治疗方案的制定过程。结果:临床药师利用药学专业知识,结合患儿的生理病理情况,在充分循证证据支持和知情告知下,针对嗜麦芽窄食单胞菌感染提出头孢哌酮/舒巴坦联合环丙沙星的抗菌治疗方案,有效控制了患儿的病情。结论:临床药师可成为临床治疗团队中重要的一员,在抗菌治疗方案制定过程中发挥专业作用,解决临床实际问题,为患者提供有效的个体化治疗,提高临床用药的安全性与有效性。

Objective： To probe into the significance of participation of clinical pharmacists in antibacterial therapy for multi-drug resistant bacteria in special populations. Methods： For a case of premature infants infected by Stenotrophomonas Maltophilia,clinical pharmacists participated in to the formulation of antimicrobial therapeutic regimen. Results： In consideration of physiological and pathological conditions of the infant,under sufficient evidence-based evidence and informed notification,clinical pharmacists put forward antibacterial therapy of cefoperazone/sulbactam combined with ciprofloxacin against S. Maltophilia infection,the diseases had been effectively controlled. Conclusion： As an important member of the clinical treatment team,clinical pharmacists play a professional role in the formulation of antibacterial therapeutic regimen,solve the clinical practical problems,provide effective individualized treatment for the patients and improve the safety and effectiveness of clinical medication.