Bowen病64例临床与病理分析

Clinical and Pathological Analysis of 64 Cases of Bowen Disease

目的探讨Bowen病的临床、组织病理学特点及其治疗方法。方法回顾性分析64例Bowen病的临床及组织病理资料。结果 Bowen病患者发病年龄较大,病程较长,男女比例为1∶1. 06,皮损非暴露部位多发。临床诊断时容易与脂溢性角化病、基底细胞癌、乳房外湿疹样癌等疾病混淆。病理学改变有其特异性。主要治疗方法为手术治疗。结论组织病理学在Bowen病的诊断过程中发挥重要作用,治疗首选手术切除。

Objective To study the clinical and histopathological features and treatment of Bowen disease. Methods The clinical and histopathological data of 64 cases of Bowen were analyzed retrospectively. Results The onsetage of Bowen patients was relatively high, the course of disease was long, the male to female ratio of cases was 1 ： 1.06, and skin lesions often appeared in the non-exposed areas. Bowen is quite easy to be confused with seborrheic keratosis, basal cell carcinoma and extramammary eczematoid carcinoma. Pathological change of Bowen is special. The main treatment is surgiealresection. Conclusion Histopathology plays an important role in diagnosing Bowen disease, and the first choice of treatment is surgery.