肝硬化患者肠系膜上动脉血流动力学变化的观测

STUDY ON THE HEMODYNAMICS OF SUPERIOR MESENTERIC ARTERY IN PATIENTS WITH CIRRHOSIS

目的 通过肝硬化肠系膜上动脉(SMA)血流动力学观测,探讨肝硬化腹水形成机理.方法 采用彩色多普勒超声对50例对照组和80例肝硬化组SMA血流动力学进行测定.结果 肝硬化代偿期患者、失代偿期患者SMA的脉动指数(PI)和阻力指数(RI)均较正常对照组明显降低,但有腹水的肝硬化又较不伴腹水者PI显著降低,且有随食道静脉曲张的加重而降低的趋势.结论肝硬化患者早期即有内脏血流阻力的减低,SMA的高动力与腹水的形成、食道静脉曲张有关.

Objective: To study superior mesenteric artery hemodynamics in patients with hepatic cirrhosis and to investigate the mechanism of hepatic cirrhosis ascites. Methods: superior mesenteric artery hymodynamics were measured py duplex Doppler ultrasound in 80 patients with hepatic cirrhosis,50 control supjects. Results: Both SMA-Pl and SMA-Rl in patients with hepatic cirrhosis compensation or decompensation were decreased. SMA-Pl was lower in those with ascites without ascites. and tends to worsen in relation to severity of varicosity in esophagus. Conclusion: SMA-Pl decrease occurs in cirrhosis since the early stage of the disease. Hyperdynamics of SMA relates to ascites formation and esophageal varicecosity.