无过渡金属参与的羰基化反应进展

Research Progress in Transition-Metal-Free Carbonylation Reactions

一氧化碳是来源广泛和廉价的碳一资源.直接将其作为羰基源引入有机分子中的羰基化反应是化学化工研究的前沿领域之一.近年来,无过渡金属参与的羰基化反应引起了人们的高度关注.综述了无过渡金属参与的羰基化合成醛与酮、合成酯、合成酰胺、合成酸和酸酐以及合成酰氯和醇等重要羰基化反应的研究现状,并对无过渡金属参与的羰基化反应的发展及应用前景进行了展望.

Carbon monoxide is a readily available and cheap C1 feedstock. Carbonylation, the direct incorporation of carbon monoxide into organic molecules, is a very important and fundamental chemical transformation. In recent years, developing transition-metal-free systems for the carbonylation has attracted highly attention from many researchers. The recent rearch progress of transition-metal-free carbonylations for the synthesis of aldehydes, ketones, esters, amides, acids, anhydrides, acyl chloride, and alcohols is reviewed. And the development and application prospects for transition-metal-free carbonylation are also discussed.