多索茶碱与氨茶碱治疗支气管哮喘临床疗效的对比观察

Comparative Observation of the Clinical Efficacy of Doxofylline and Aminophylline in the Treatment of Bronchial Asthma

目的探讨多索茶碱与氨茶碱治疗支气管哮喘临床疗效及对比观察。方法对以往接收过支气管哮喘患者作为研究对象,该院从2015—2017年共入院治疗支气管哮喘患者数量60例,这60例患者均符合支气管哮喘相关标准,其中60例支气管哮喘患者中有女性18例,男性42例,整体年龄小于30岁为28例,30～45岁之间为22例,大于45岁为10例患者。整体平均年龄在(33.8±5.9)岁。并随机平分分配两组,每组人数为30例,将其定义实验1组和实验2组。实验1组进行氨茶碱药物治疗,而实验2组进行多索茶碱药物治疗,主要通过一个治疗阶段进行比较,然后进行数据分析。结果接收过60例支气管哮喘患者进行分析后,这些患者均有好转,而实验2组患者在治疗后,显效8例(26.7%)有效为10例(33.3%),总有效率为60.0%。而实验1组患者在治疗后,显效为12例(40.0%),有效为15例(50.0%),总有效率为90.0%。通过两组比对后,均没有产生严重不良反应,通过治疗后有不良反应患者都可以自行调节,调节后均为正常表现。结论通过对接收支气管哮喘患者进行分析后得知,多索茶碱药物与氨茶碱药物可以有效治疗支气管哮喘患者,并提高治疗效率,而不良反应几乎没有,而多索茶碱比氨茶碱药物治疗效果好,所以多索茶碱药物需要大力进行临床发展。

Objective To investigate the clinical efficacy and comparative observation of doxofylline and aminophyllinein the treatment of bronchial asthma. Methods A total of 60 patients with bronchial asthma were admitted to the hospi-tal from 2015 to 2017. These 60 patients met the relevant criteria for bronchial asthma. Among them, 60 patients withbronchial asthma were women. There were 18 cases, 42 males, 28 cases were younger than 30 years old, 22 cases werebetween 30-45 years old, and 10 cases were older than 45 years old. The overall average age was （33.8〈5.9）years old.Two groups were randomly divided into groups, each group consisting of 30 persons, and the experimental group 1 andthe experimental group 2 were defined. The experimental group 1 was treated with aminophylline drugs, and the experi-mental group 2 was treated with doxofylline drugs, mainly through a treatment stage for comparison, and then data wasanalyzed. Results After receiving 60 patients with bronchial asthma, these patients improved. In the 2 experimentalgroup, 8 patients （26.7%） were very effective, 10 patients （33.3%） were effective, and the total effective rate was 60.0%.In the experimental group 1, the very effective rate was 12 case（40.0%）, and the effective rate was 15 cases（50.0%）.The total effective rate was 90.0%. After the two groups were compared, no serious adverse reactions were produced.Patients who had adverse reactions after treatment were able to adjust themselves and were normal after adjustment.Conclusion By analyzing the patients receiving bronchial asthma, it is known that doxofylline and aminophylline caneffectively treat bronchial asthma patients and improve the treatment efficiency, while the adverse reactions are almostno, while doxofylline is more than aminophylline. The drug treatment effect is good, so the doxofylline drug needs to bevigorously developed clinically.