焦作市2017年无偿献血谷丙转氨酶初筛浅析

Analysis on the Preliminary Screening of Alanine Aminotransferase in Blood Donation in Jiaozuo City in 2017

目的了解该市无偿献血人群谷丙转氨酶初筛不合格原因,为满足该市临床安全用血,制定招募宣教计划、保证安全血源的策略提供有效依据。方法采集2017年1月—12月焦作市自愿无偿献血者9个采血点47 586人份血液标本(全血45 018人次机采2 568人次)进行谷丙转氨酶初筛检测,并按全血成分血献血类型、性别、体重指数和初、再次献血情况运用统计学方法进行分析。结果成分献血(机采血小板)阳性比例明显低于全血捐献者,性别上男性谷丙转氨酶阳性率明显高于女性,肥胖(BMI≥28 kg/m^2)谷丙转氨酶阳性率呈现明显上升趋势,再次献血者谷丙转氨酶阳性率明显低于初次献血者。结论有针对性地加强不同献血者献血前宣传教育和征询,献血前谷丙转氨酶初筛检测非常必要,能有效降低血液报废率,节约宝贵的血液资源,满足临床用血安全。

Objective To understand the reasons for the unsatisfactory screening of alanine aminotransferase in the unpaid blood donation population in our city, and to provide an effective basis for the strategy of recruiting mission plans and ensuring safe blood sources in order to meet the clinical safety blood consumption of our city. Methods From January to December 2017, the voluntary blood donors in Jiaozuo City, 9 blood collection points, 47 586, blood samples （the whole blood, 45 018 people, 2 568 person-times）were taken for the initial screening test of alanine aminotransferase. According to the blood type, sex, body mass index and initial and re-blood donation of whole blood components, statistical methods were used for analysis. Results The positive proportion of blood donation （mechanical platelet count） was significantly lower than that of whole blood donors. The positive rate of male alanine aminotransferase was significantly higher than that of female. The positive rate of obesity（BMI≥ 28 kg/m2） alanine aminotransferase showed a significant upward trend. The positive rate of alanine aminotransferase was significantly lower than that of the first blood donor. Conclusion Targeted education and con- sultation before blood donation of blood donors are strengthened. It is necessary to test the initial screening of alanine aminotransferase before blood donation, which can effectively reduce the blood scrap rate, save valuable blood resources and meet the safety of clinical blood.