中西医结合治疗反流性食管炎肝胃不和证临床观察

Clinical Observation on Treatment of Reflux Esophagitis with Stagnation of Liver and Stomach

目的研究分析反流性食管炎肝胃不和证患者应用中西医结合疗法治疗的临床效果。方法该次研究方便选取于2016年4月—2017年4月该院纳入70例肝胃不和证患者,随机对照分组,每组35例,对照组患者给予西药治疗,服用埃索美拉唑肠溶胶囊,观察组患者给予中西医结合治疗,在服用埃索美拉唑肠溶胶囊的基础上给予舒肝和胃丸,参考胃镜检查下情况及患者临床症状进行评价,在治疗前和治疗后进行积分评价。结果观察组患者总有效率为97.1%,明显高于对照组患者总有效率74.3%,组间比较数据差异有统计学意义(X^2=7.467,P<0.05),在治疗前两组患者症状评分比较差异无统计学意义(P>0.05),在治疗后观察组患者症状评分中,反酸(0.67±0.25)分、烧心(0.66±0.21)分、胸痛(0.70±0.12)分、嗳气(0.51±0.23)分、吞咽困难(0.27±0.15)分低于对照组患者,组间差异有统计学意义(t=3.982、4.012、4.023、3.997、4.111,P<0.05)。结论埃索美拉唑肠溶胶囊联合舒肝和胃丸应用中西医结合疗法治疗反流性食管炎的临床效果显著,值得在临床中推广应用。

Objective To analyze the clinical effects of integrated traditional Chinese and Western medicine therapy in patients with reflux esophagitis and liver-stomach syndrome. Methods From April 2016 to April 2017, the hospital included70 patients with liver-stomach disharmony syndrome were conveniently selected. The randomized control group consisted of35 patients in each group. The control group received western medicine treatment and took esomeprazole enteric-coated capsules. The patients in the observation group were treated with integrated Chinese and Western medicine. The patients were given Shuganhewei pill on the basis of taking esomeprazole enteric-coated capsules. The patients under the gastroscopy and the clinical symptoms were evaluated. The scores were scored before and after treatment. Results The total effective rate of the observation group was 97.1%, which was significantly higher than that of the control group（74.3%）. The difference between the two groups was significant（X^2=7.467, P〈0.05）. There was no statistical difference in the symptom scores between the two groups before treatment. The significance of learning（P〉0.05）, in the symptom score of the observation group after treatment, acid reflux（0.67±0.25）points, heartburn（0.66±0.21）points, chest pain（0.70±0.12）points, and hernia（0.51±0.23）points dysphagia（0.27±0.15）points was lower than that of the control group, and the difference between the groups was statistically significant（t =3.982, 4.012, 4.023, 3.997, 4.111, P 〈0.05）. Conclusion The clinical effect of esomeprazole enteric-coated capsule combined with Shuganhewei pill in the treatment of reflux esophagitis with traditional Chinese medicine and western medicine is significant and worthy of popularization and application in clinic.