磁共振评价慢性心力衰竭患者右心结构及功能的临床研究

Clinical research on MRI evaluating right heart structure and function in patients with chronic heart failure

目的研究心脏磁共振在慢性心力衰竭(CHF)右心结构及功能评价中的应用价值。方法选择2016年1月～2017年12月成都市第五人民医院收治的CHF患者32例作为观察组,另选择同期体检的健康者32名作为对照组。两组均行CMR检查,比较两组的右心结构及功能指标,包括右室侧壁厚度(RVT)、右室侧壁质量(RVM)、右室乳头肌质量(RVPM)、右室舒张末期容积(RVEDV)、右室收缩末期容积(RVESV)、右室每搏输出量(RVSV)、右室射血分数(RVEF)。结果观察组的右心室RVT、RVM、RVPM、RVEDV、RVESV和RVSV较对照组明显升高,RVEF较对照组明显降低,差异有统计学意义(P <0.05或P <0.01)。结论 CMR可定量分析CHF患者右心室结构和功能,有助于判断患者疾病进展情况。

Objective To study the value of cardiac magnetic resonance （CMR） in the evaluation of right heart structure and function in chronic heart failure. Methods From January 2016 to December 2017, in the Fifth People′s Hospital of Chengdu, 32 patients with CHF were chosen as observation group, another 32 healthy person who received physical examination at the same period were chosen as control group. CMR examination was performed in both groups, and the right heart structure and function indexes of two groups were compared, such as right ventricular thickness （RVT）, right ventricular mass （RVM）, right ventricular papillary muscle mass （RVPM）, right ventricular end diastolic volume （RVEDV）, right ventricular systolic volume （RVESV）, right ventricular stroke volume （RVSV）, right ventricular ejection fraction （RVEF）. Results The RVT, RVM, RVPM, RVEDV, RVESV and RVSV of the right ventricle in the observation group were significantly higher than those in the control group, the RVEF was significantly lower than that in the control group, the differences were statistically significant （P 〈 0.05 or P 〈 0.01）. Conclusion CMR can quantitatively analyze the right ventricular structure and function of patients with CHF, which helps to determine the patients′ disease progression.