维生素D与甲状腺疾病的相关研究进展

Research Progress of Vitamin D and Thyroid Diseases

维生素D在人体骨钙代谢平衡中具有重要作用,同时还具有骨骼外作用,它是一种新免疫调节激素,几乎在所有身体组织中均可能产生影响,其中维生素D与甲状腺疾病的关系密切。目前,国内外对Graves病及桥本甲状腺炎的基础及临床研究较为关注,尤其是维生素D缺乏与其患病率有一定的相关性,但其在预防及治疗上的价值仍需进一步研究。同时,虽然维生素D在抗肿瘤治疗中的作用已被认可,但其与甲状腺癌的研究相对较少,未来需要广泛的试验来探索两者之间的关系及作用机制。

Vitamin D plays an important role in the balance of bone calcium metabolism and also has some non-skeletal effects. It is a newly discovered immunoregulatory hormone and may affect almost all body tissues.Among them,vitamin D is closely related to thyroid disease.At present,the basic and clinical research on Graves disease and Hashimoto thyroiditis are concerned at home and abroad,especially that the vitamin D deficiency has a certain correlation with its prevalence,but its value in prevention and treatment still needs further study.At the same time,although the role of vitamin D in anti-tumor therapy has been recognized,its research on thyroid cancer is relatively rare,and extensive trials are needed in the future to explore the relationship between them and the mechanism of action.