儿童脓毒症的致病病原体及治疗的研究进展

Research Progress in Pathogen and Treatment of Pediatric Sepsis

脓毒症是一种异质性临床综合征,包括许多不同类型及严重程度的感染,是全世界儿童死亡的重要原因之一。尽管儿童脓毒症的诊断和治疗策略在很大程度上受成人脓毒症的影响,但患儿有不同于成人的独特特征。儿童脓毒症的管理必须根据儿童的年龄、机体的免疫能力、感染部位、严重程度以及感染来源进行调整。因此了解儿童脓毒症的常见病原体、流行病学特点以及治疗策略对于调整诊治策略,改善患儿预后,降低病死率,减少残疾至关重要。

Sepsis is a heterogeneous clinical syndrome that encompasses many different types of infections with different severities,and is one of the major causes of child death worldwide.Although diagnosis and treatment strategies for pediatric sepsis are largely influenced by adult sepsis,children have own unique characteristics different from adults.The management of pediatric sepsis must be tailored to the child′s age,immune capacity,infection site,severity,and source of the infection.So,it is important for the clinicians to be aware of common pathogens and epidemiological characteristics,and adjust the diagnosis and treatment strategies to reduce the disability and mortality caused by sepsis and improve the prognosis.